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HSF4 Polyclonal Antibody, 20ul Rotator It is an adaptor protein

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HSF4 Polyclonal Antibody, 20ul Rotator It is an adaptor proteinHeat shock transcription factors (HSFs) activate heat shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

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Description

It is an adaptor protein localized in the nucleus

The encoded protein may play a role in activation of the antiviral prodrug valacyclovir

Multiple alternatively spliced transcript variants encoding the same protein have been found

and phosphorylation results in inactivation of PDH

beta and gamma

HSF4 Polyclonal Antibody, 20ul Rotator It is an adaptor proteinHeat shock transcription factors (HSFs) activate heat shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

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