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Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation specifically require this kinase

SKU: 7666208045

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Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation specifically require this kinaseRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

specifically require this kinase

including breast and ovarian tumors

this kinase translocates to the nucleus of the stimulated cells

GO annotations related to this gene include G-protein coupled receptor activity

The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2

Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation specifically require this kinaseRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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