Beclin-1 mouse Monoclonal Antibody(5C2), 100ul Peripheral Blood Separation Tube The protein encoded by KCNK17

The protein encoded by KCNK17 (potassium two pore domain channel subfamily K member 17) belongs to the family of potassium channel proteins containing two pore-forming P domains

This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis

CSNK1A1 phosphorylates CTNNB1 at Ser-45

Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner

Three members of this gene family have been studied in detail and are estimated to generate over 3000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member

Beclin-1 mouse Monoclonal Antibody(5C2), 100ul Peripheral Blood Separation Tube The protein encoded by KCNK17This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.