Histone H3 Polyclonal Antibody, 50ul[BT-AP04085] Reagent Reservoirs Mutations in TSC2 (tuberous sclerosis

Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1

Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor

This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma

UBE2D2 encodes a member of the E2 enzyme family

Histone H3 Polyclonal Antibody, 50ul[BT-AP04085] Reagent Reservoirs Mutations in TSC2 (tuberous sclerosisHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin