SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production compared to 6-39 in the

compared to 6-39 in the normal allele

Has a two domain structure: the G-domain binds GTP

BRSK1 plays an essential role in neuronal polarization and may be involved in regulating cell cycle arrest in response to DNA damage

This protein may also function independently of dynein as a transcriptional modulator

and they are implicated in synaptogenesis and the modulation of neurotransmitter release

SQSTM1/p62(Phospho-Ser349) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production compared to 6-39 in theThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in