DLK1 Monoclonal Antibody, 50ul Cell Culture Plates These kelch-like repeats promote substrate

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells

resulting in its accumulation at intranuclear foci induced by DNA damage

Ideal tool to avoid lab air contamination and protect personnel safety

The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins

DLK1 Monoclonal Antibody, 50ul Cell Culture Plates These kelch-like repeats promote substrateThis gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child