p15 Polyclonal Antibody, 20ul Thermo Mix This gene family contains numerous

This gene family contains numerous pseudogenes

The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor

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Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease)

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p15 Polyclonal Antibody, 20ul Thermo Mix This gene family contains numerousCDKN2B lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B encodes a cyclin dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus cyclin dependent kinase inhibitor 2B functions as a cell growth regulator that controls cell cycle G1 progression. The expression of CDKN2B was found to be dramatically