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PEA-15(Phospho Ser104) Polyclonal Antibody, 100ul Dry Bath It has a catalytic PTP

SKU: 75046444626

4.2
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PEA-15(Phospho Ser104) Polyclonal Antibody, 100ul Dry Bath It has a catalytic PTPThis gene encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements

Phosphorylated on upon DNA damage| probably by ATM or ATR

The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors

14-dihydro-prostaglandin E2

It is involved in energy metabolism

PEA-15(Phospho Ser104) Polyclonal Antibody, 100ul Dry Bath It has a catalytic PTPThis gene encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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