Presenilin 2(Phospho Ser330) Polyclonal Antibody, 50ul Cell Screening and Imaging RAB3 GTPase activating non-catalytic protein

RAB3 GTPase activating non-catalytic protein subunit 2 forms the Rab3 GTPase-activating complex with RAB3GAP1

insulin-resistant individuals

The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein

Easy to operate

|subcellular location:Present in lipid rafts

Presenilin 2(Phospho Ser330) Polyclonal Antibody, 50ul Cell Screening and Imaging RAB3 GTPase activating non-catalytic proteinAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP. Also,