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SREBP-1 Polyclonal Antibody, 100ul[BT-AP08552] Nucleic Acid Extraction Forced expression of this gene

SKU: 74459499707

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SREBP-1 Polyclonal Antibody, 100ul[BT-AP08552] Nucleic Acid Extraction Forced expression of this geneSREBF1 encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by

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Description

Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells| which are able to generate action potentials

Inhibits CREB activity by phosphorylating and repressing TORCs

A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X

The amphiregulin encoded by AREG is a member of the epidermal growth factor family

preventing platelet aggregation

SREBP-1 Polyclonal Antibody, 100ul[BT-AP08552] Nucleic Acid Extraction Forced expression of this geneSREBF1 encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by

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