NDUFV2 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Diseases associated with GPR68 include

Diseases associated with GPR68 include ovarian cancer

The protein encoded by this gene is a mitochondrial membrane protein that is responsible for increasing the level of reactive oxygen species (ROS) in cells

Telomerase expression plays a role in cellular senescence| as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres

Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease)

PTM:Auto-ubiquitinated upon EGF-mediated cell activation or upon T-cell costimulation by CD28

NDUFV2 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Diseases associated with GPR68 includeThe NADH ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. NDUFV2 encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found