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FA58A Polyclonal Antibody, 20ul Supplements Multiple pseudogenes of CTSB have

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FA58A Polyclonal Antibody, 20ul Supplements Multiple pseudogenes of CTSB haveMutations in this gene have been shown to cause an X linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin box fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Description

Multiple pseudogenes of CTSB have been identified

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Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus

This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling

is a lysosomal cysteine proteinase that may play an important role in corneal physiology

FA58A Polyclonal Antibody, 20ul Supplements Multiple pseudogenes of CTSB haveMutations in this gene have been shown to cause an X linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin box fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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