beta -Arrestin 1(Phospho-Ser412) Rabbit Polyclonal Antibody, 20ul Drying & Desiccation and one delta subunit

and one delta subunit

that are equally active

Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases

The first exon of this gene is unrelated to immunoglobulin variable genes

but the full-length nature of only some of these variants has been described

beta -Arrestin 1(Phospho-Ser412) Rabbit Polyclonal Antibody, 20ul Drying & Desiccation and one delta subunitMembers of arrestin beta arrestin protein family are thought to participate in agonist mediated desensitization of G protein coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones neurotransmitters or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta adrenergic receptor kinase (BARK) mediated desensitization of beta adrenergic receptors. Besides the central nervous