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Six3/6 Polyclonal Antibody, 100ul Protein Expression It was found to be

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Six3/6 Polyclonal Antibody, 100ul Protein Expression It was found to beHomeobox protein SIX6 encoded by SIX6 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).

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Description

It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15)

This gene encodes a member of the semaphorin family of proteins

The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting

and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD)

The exact role of this gene has not been determined

Six3/6 Polyclonal Antibody, 100ul Protein Expression It was found to beHomeobox protein SIX6 encoded by SIX6 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).

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