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EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 50ul Liquid Handling &Storage CDON encodes a cell surface

SKU: 72676815

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EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 50ul Liquid Handling &Storage CDON encodes a cell surfaceThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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Description

CDON encodes a cell surface receptor that is a member of the immunoglobulin superfamily

an octamer composed of pairs of each of the four core histones (H2A

|tissue specificity:Leukemic stem cell

Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis

A recent study showed this gene to be an authentic stop codon readthrough target| and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon

EKLF (Acetyl Lys274) Rabbit Polyclonal Antibody, 50ul Liquid Handling &Storage CDON encodes a cell surfaceThis gene encodes a hematopoietic specific transcription factor that induces high level expression of adult beta globin and other erythroid genes. The zinc finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss of function mutations in this gene result in the dominant In(Lu) blood phenotype.

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