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Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter which involves increased risk of

SKU: 72507314614

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Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter which involves increased risk ofPOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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Description

which involves increased risk of cancers including malignant mesothelioma

where they participate in a wide range of physiologic responses

The protein encoded by this gene is a member of the insulin-like growth factor family of signaling molecules

while the HLH domain facilitates the mono- and heterodimeric interactions required for efficient DNA binding

Variations in this gene have been linked to metabolic syndrome

Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter which involves increased risk ofPOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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