RFA4 Polyclonal Antibody, 50ul Multiplex Immunoassays Translocation of portions of chromosome

Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas

This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells

PBK (PDZ binding kinase) encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family

This kinase can be activated by TNF-alpha

The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal

RFA4 Polyclonal Antibody, 50ul Multiplex Immunoassays Translocation of portions of chromosomeThis gene encodes a single stranded DNA binding protein that is the 30 kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.