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MIS Polyclonal Antibody, 100ul Miscellaneous The encoded preproprotein present in

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MIS Polyclonal Antibody, 100ul Miscellaneous The encoded preproprotein present inThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N and C terminal cleavage products that homodimerize and associate to form a biologically active noncovalent

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Description

The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked

The encoded protein is a highly specific ubiquitin iso-peptidase

This protein possesses histone deacetylase activity and represses transcription

It is preferentially an oxidative enzyme and inactivates estradiol

while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease

MIS Polyclonal Antibody, 100ul Miscellaneous The encoded preproprotein present inThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N and C terminal cleavage products that homodimerize and associate to form a biologically active noncovalent

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