MEK2 Rabbit Polyclonal Antibody, 50ul Cellular Function Assays The splicing factor 3b/3a complex

The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA

The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain

The protein contains a large number of acidic domains

an ATP-dependent multisubunit protein that activates the proteolytic activities of the multifunctional proteinase (20S proteasome) of the 26S complex

Among its related pathways are Metabolism and Glycerophospholipid biosynthesis

MEK2 Rabbit Polyclonal Antibody, 50ul Cellular Function Assays The splicing factor 3b/3a complexThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1 ERK2 and MAPK2 ERK3. The activation of this kinase itself is dependent on the Ser Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC