M-CSF Monoclonal Antibody, 100ul Enzymes The identity of the growth

The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer

2004 [PubMed 15153109])

Alternative splicing results in two isoforms where the shorter isoform

and the two encoded proteins are thought to associate with each other to form heteromeric channels

Also interacts with mutant SOD1

M-CSF Monoclonal Antibody, 100ul Enzymes The identity of the growthThe protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide linked homodimer, and is thought to be produced by proteolytic cleavage of membrane bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.