Raf-1(Phospho Ser621) Polyclonal Antibody, 20ul Cell Culture RPS6KA1 (ribosomal protein S6 kinase

RPS6KA1 (ribosomal protein S6 kinase A1) encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases

C-terminal

The encoded protein is primarily expressed in the epidermis| and plays a critical role in keratinocyte proliferation and differentiation

Specific isoforms bind to alpha-dystroglycan and to alpha-latroxin

the helix-loop-helix (HLH) proteins

Raf-1(Phospho Ser621) Polyclonal Antibody, 20ul Cell Culture RPS6KA1 (ribosomal protein S6 kinaseThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.