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Phospho-Cbl (Y674) Polyclonal Antibody, 50ul PCR Series Mutations in this gene have

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Phospho-Cbl (Y674) Polyclonal Antibody, 50ul PCR Series Mutations in this gene haveCBL (Cbl proto oncogene) is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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Description

Mutations in this gene have been associated with Laron syndrome

many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF

The SOCS box domain mediates the interaction with the Elongin BC complex

Expression of this particular cadherin in osteoblastic cell lines

This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane

Phospho-Cbl (Y674) Polyclonal Antibody, 50ul PCR Series Mutations in this gene haveCBL (Cbl proto oncogene) is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated

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