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ETBR Polyclonal Antibody, 50ul Lentiviral Packaging The encoded protein acts on

SKU: 71141799472

4.5
PLN162.00 PLN183.00

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ETBR Polyclonal Antibody, 50ul Lentiviral Packaging The encoded protein acts onThe protein encoded by EDNRB (endothelin receptor type B) is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding

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Description

The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins

Several transcript variants encoding the same protein have been found for this gene

and has a preferred 5-kinase activity

However| the requirement for furin cleavage in this process remains controversial based on mouse studies

This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU)

ETBR Polyclonal Antibody, 50ul Lentiviral Packaging The encoded protein acts onThe protein encoded by EDNRB (endothelin receptor type B) is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding

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