TPH1(Phospho Ser260) Polyclonal Antibody, 50ul Custom DNA Oligos May play an essential role

May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery

This gene is expressed in the thymus and in several epithelial structures early in embryogenesis

Diseases associated with GPR68 include ovarian cancer

Localized to endosomes and endoplasmic reticulum of the perinuclear region

Higher expression of this protein has also been reported in brain

TPH1(Phospho Ser260) Polyclonal Antibody, 50ul Custom DNA Oligos May play an essential roleThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.