IP3R-I(Phospho Ser1598) Polyclonal Antibody, 100ul Long RNA Synthesis PubMed: 19131338

PubMed: 19131338

This protein is a component of anaphase-promoting complex (APC)

and gamma subunits

A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines

and transfers it to substrates

IP3R-I(Phospho Ser1598) Polyclonal Antibody, 100ul Long RNA Synthesis PubMed: 19131338This gene encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.