ERK 5 Polyclonal Antibody, 100ul[BT-AP15460] Enzyme Activity Assays Frequent amplification of this gene

Frequent amplification of this gene has been found in human tumors

This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family

Mutations in ABCB7 have been associated with mitochondrial iron accumulation and isodicentric (X) (q13) and sideroblastic anemia

CTNND1 (catenin delta 1) encodes a member of the Armadillo protein family

which have been implicated in childhood lymphoblastic leukemia

ERK 5 Polyclonal Antibody, 100ul[BT-AP15460] Enzyme Activity Assays Frequent amplification of this geneThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen activated protein kinase kinase 5 (MAP2K5 MEK5). It is involved in the downstream signaling processes of various receptor