PLEK2 Rabbit Polyclonal Antibody, 100ul Roller Bottles Also component of the mSin3A

Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones

including gene expression

Each bottle contains 50 L of solution

Expression of this protein is induced during recovery following starvation

Mutations in PRKAR1A cause Carney complex (CNC)

PLEK2 Rabbit Polyclonal Antibody, 100ul Roller Bottles Also component of the mSin3AThe protein encoded by this gene associates with membrane bound phosphatidylinositols generated by phosphatidylinositol 3 kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1 q subcomponent B chain (C1QB) this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease.