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Phospho-14-3-3 Zeta (S58) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds |Contains 1 peptidase S1 domain

SKU: 69618568747

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Phospho-14-3-3 Zeta (S58) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds |Contains 1 peptidase S1 domainTyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta belongs to the 14 3 3 family of proteins which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. Tyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta interacts with IRS1 protein,

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Description

|Contains 1 peptidase S1 domain

also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19)

Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases

tissue expression and substrate preference

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs)

Phospho-14-3-3 Zeta (S58) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds |Contains 1 peptidase S1 domainTyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta belongs to the 14 3 3 family of proteins which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. Tyrosine 3 monooxygenase tryptophan 5 monooxygenase activation protein zeta interacts with IRS1 protein,

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