Cdk5 Monoclonal Antibody, 100ul[BT-MCA0332] CellSafe™ Transcription of protein-coding genes can

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II

It contains an N-terminal caspase recruitment domain (CARD)| a centrally located nucleotide-binding domain (NBD)| and 10 tandem leucine-rich repeats (LRRs) in its C terminus

The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance

Mutations of ankyrin genes lead to severe genetic diseases

Before ligand binding

Cdk5 Monoclonal Antibody, 100ul[BT-MCA0332] CellSafe™ Transcription of protein-coding genes canThis gene encodes a proline directed serine threonine kinase that is a member of the cyclin dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration