GPR135 Polyclonal Antibody, 50ul Molecular Biology Some modulators interact directly with

Some modulators interact directly with the basal complex

Four transcript variants encoding three different isoforms have been found for this gene

Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain

This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells

Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease

GPR135 Polyclonal Antibody, 50ul Molecular Biology Some modulators interact directly withGPR135 (G Protein Coupled Receptor 135) is a Protein Coding gene. Among its related pathways are GPCRs, Other. GO annotations related to this gene include G protein coupled receptor activity. An important paralog of this gene is GPR45.