DNJC3 Polyclonal Antibody, 20ul Centrifuges Related pseudogenes exist on chromosomes

Related pseudogenes exist on chromosomes 2 and X

Diseases associated with GPR176 include waterhouse-friderichsen syndrome

both of which are the potent inducers of cell apoptosis

Three transcript variants encoding different isoforms have been found for AKR1C3

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

DNJC3 Polyclonal Antibody, 20ul Centrifuges Related pseudogenes exist on chromosomesThis gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon induced, dsRNA activated protein kinase (PKR).