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Smad3 mouse Monoclonal Antibody(4C9), 100ul Cell Culture Additional isoforms produced by alternative

SKU: 67319285558

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Smad3 mouse Monoclonal Antibody(4C9), 100ul Cell Culture Additional isoforms produced by alternativeThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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Description

Additional isoforms produced by alternative splicing seem to exist

which is required for synaptic vesicle docking and fusion

Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency

|Belongs to the DNA glycosylase MPG family

and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region

Smad3 mouse Monoclonal Antibody(4C9), 100ul Cell Culture Additional isoforms produced by alternativeThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of

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