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CD63 Polyclonal Antibody, 50ul[BT-AP01927] Diagnostic Probes & Oligos The encoded calcium-dependent enzyme catalyzes

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CD63 Polyclonal Antibody, 50ul[BT-AP01927] Diagnostic Probes & Oligos The encoded calcium-dependent enzyme catalyzesF13A1 encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of

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Description

The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids

and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects

The exact function of this gene is not known| but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins| including inflammatory mediators

Mutations in this gene are associated with gastrointestinal stromal tumors| mast cell disease| acute myelogenous lukemia| and piebaldism

Contains 1 PID domain

CD63 Polyclonal Antibody, 50ul[BT-AP01927] Diagnostic Probes & Oligos The encoded calcium-dependent enzyme catalyzesF13A1 encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of

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