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BAGE2 Polyclonal Antibody, 50ul[BT-AP06667] Site-directed Mutagenesis Members of this family encode

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BAGE2 Polyclonal Antibody, 50ul[BT-AP06667] Site-directed Mutagenesis Members of this family encodeUnknown. Candidate gene encoding tumor antigens.,miscellaneous: The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes,

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Description

Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins

Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells

These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity

This receptor also binds to various TRAF family members

A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility

BAGE2 Polyclonal Antibody, 50ul[BT-AP06667] Site-directed Mutagenesis Members of this family encodeUnknown. Candidate gene encoding tumor antigens.,miscellaneous: The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes,

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