TAL1 Polyclonal Antibody, 50ul Molecular Sciences Defects in this gene are

Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS)

Mutations in this gene can cause X-chromosomal non-specific mental retardation

An important paralog of this gene is MAP4K3

and plays a role in antigen presentation

The protein kinase encoded by CDK11A can be cleaved by caspases and may play a role in cell apoptosis

TAL1 Polyclonal Antibody, 50ul Molecular Sciences Defects in this gene areThe basic helix loop helix (bHLH) family of transcription factors play roles in a variety of developmental and adult biological settings. The basic (b) domain of bHLH transcription factors allows association with DNA, while the HLH domain facilitates the mono and heterodimeric interactions required for efficient DNA binding. TAL1, also known as SCL, is a bHLH transcription factor that plays an essential role in the generation of embryonic