PHC3 Polyclonal Antibody, 20ul Peptide Modification RanGTP binds importin-beta and displaces
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PHC3 Polyclonal Antibody, 20ul Peptide Modification RanGTP binds importin-beta and displacesComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys 119', rendering chromatin heritably changed in its expressibility.,PTM: Phosphorylated upon DNA damage, probably by ATM or
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