c-Fgr Monoclonal Antibody, 100ul Plasmid Preparation Two transcript variants encoding the

Two transcript variants encoding the same protein have been found for this gene

Several transcript variants encoding many different isoforms have been found for EDA

The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs)

in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor

When overexpressed

c-Fgr Monoclonal Antibody, 100ul Plasmid Preparation Two transcript variants encoding theThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein protein interactions with phosphotyrosine containing and proline rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion