FoxO4(Phospho Ser262) Polyclonal Antibody, 50ul Variant Libraries Contraction of the macrosatellite repeat

Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD)

which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons

both anchored in the membrane

process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction

subcellular location:Mainly cytoplasmic

FoxO4(Phospho Ser262) Polyclonal Antibody, 50ul Variant Libraries Contraction of the macrosatellite repeatThis gene encodes a member of the O class of winged helix forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants