Paxillin Polyclonal Antibody, 100ul[BT-AP06956] Cell Labeling & Imaging The Kell glycoprotein links via

The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen

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Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP

Mutations in LMNA lead to several diseases: emery-Dreifuss muscular dystrophy

encoding nearly 900 genes

Paxillin Polyclonal Antibody, 100ul[BT-AP06956] Cell Labeling & Imaging The Kell glycoprotein links viaPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.