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SAMHD1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases HELZ2 is a member of

SKU: 63568330825

4.3
SEK123.75 SEK151.75

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SAMHD1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases HELZ2 is a member ofSAMHD1 may play a role in regulation of the innate immune response. The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi Goutieres syndrome.

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Description

HELZ2 is a member of the DNA2/NAM7 helicase gene family

binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410)

POLA1 encodes the catalytic subunit of DNA polymerase

This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation

This gene encodes one of the mitochondrial translation elongation factors

SAMHD1 Polyclonal Antibody, 100ul Endonucleases & Exonucleases HELZ2 is a member ofSAMHD1 may play a role in regulation of the innate immune response. The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi Goutieres syndrome.

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