Smad4 Polyclonal Antibody, 50ul RNA Tools and a modulator of CDK2

and a modulator of CDK2 kinase activity via p21

The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner

This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea

This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family| whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains

The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases

Smad4 Polyclonal Antibody, 50ul RNA Tools and a modulator of CDK2SMAD4 encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine threonine receptor kinases in response to TGF beta signaling. The product of SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8 bp