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Fhit(Phospho Tyr114) Polyclonal Antibody, 20ul Enzymes & Activity Assays The product of this gene

SKU: 62526360668

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Fhit(Phospho Tyr114) Polyclonal Antibody, 20ul Enzymes & Activity Assays The product of this geneThis gene, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively

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Description

The product of this gene plays a major role in growth and in skin

but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase

|subcellular location:Secreted upon association with IL12B

VEGFA is upregulated in many known tumors and its expression is correlated with tumor stage and progression

Two transcript variants encoding different isoforms have been found for NME1

Fhit(Phospho Tyr114) Polyclonal Antibody, 20ul Enzymes & Activity Assays The product of this geneThis gene, a member of the histidine triad gene family, encodes a diadenosine 5',5''' P1,P3 triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively

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