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PEBP2Beta Polyclonal Antibody, 100ul NGS Oligos also known as HP43

SKU: 61530783541

4.6
USD141.00 USD163.00

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PEBP2Beta Polyclonal Antibody, 100ul NGS Oligos also known as HP43Core binding factor beta subunit encoded by CBFB is the beta subunit of a heterodimeric core binding transcription factor belonging to the PEBP2 CBF transcription factor family which master regulates a host of genes specific to hematopoiesis (e. G. RUNX1) and osteogenesis (e. G. RUNX2). The beta subunit is a non DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various

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Description

also known as HP43

It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3

VRK2 (vaccinia related kinase 2) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases

Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease

Mutations in this gene are associated with early infantile epileptic encephalopathy

PEBP2Beta Polyclonal Antibody, 100ul NGS Oligos also known as HP43Core binding factor beta subunit encoded by CBFB is the beta subunit of a heterodimeric core binding transcription factor belonging to the PEBP2 CBF transcription factor family which master regulates a host of genes specific to hematopoiesis (e. G. RUNX1) and osteogenesis (e. G. RUNX2). The beta subunit is a non DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various

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