Nkx-2.6 Polyclonal Antibody, 50ul Transporters The mammalian class C Vps

The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes| and like their yeast counterparts| may mediate vesicle trafficking steps in the endosome/lysosome pathway

Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia

The C-C motif chemokine receptor 4 encoded by CCR4 belongs to the G-protein-coupled receptor family

this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles

beta and gamma chain

Nkx-2.6 Polyclonal Antibody, 50ul Transporters The mammalian class C VpsNkx2 6 encodes a homeobox containing protein that belongs to the NK 2 homeobox family. NK2 homeobox is a vertebrate homolog of Drosophila homeobox containing protein called 'tinman', which has been shown to be essential for development of the heart like dorsal vessel. In conjunction with related gene, NKX2 5, Nkx2 6 may play a role in both pharyngeal and cardiac embryonic development. Mutations in Nkx2 6 are associated with persistent truncus