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LIMK-2(Phospho Ser283) Polyclonal Antibody, 20ul ADME |PTM:The N-terminal processed form GRO-beta(5-73)

SKU: 60583726705

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LIMK-2(Phospho Ser283) Polyclonal Antibody, 20ul ADME |PTM:The N-terminal processed form GRO-beta(5-73)There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase

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Description

|PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells

The protein encoded by THBS2 (thrombospondin 2) belongs to the thrombospondin family

The complex is also involved in phosphorylation of p53/TP53

TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity

The protein encoded by SIX1 (SIX homeobox 1)is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product

LIMK-2(Phospho Ser283) Polyclonal Antibody, 20ul ADME |PTM:The N-terminal processed form GRO-beta(5-73)There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase

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