MARH8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Guanine nucleotide exchange factor (GEF)

Guanine nucleotide exchange factor (GEF)

like RXRA and probably THRA

May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F

to form a receptor complex that mediates the action of the leukemia inhibitory factor

and the modulation of innate and adaptive immune responses

MARH8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Guanine nucleotide exchange factor (GEF)MARCH8 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003