GPR143 Polyclonal Antibody, 100ul Centrifugal Filter Several pseudogenes have been associated

Several pseudogenes have been associated with this gene

Expression of the encoded protein is able to induce apoptosis

This gene is found in a cluster with other desmoglein family members on chromosome 18

TNF-alpha causes translocation from the cytoplasm to the nucleus

Among its related pathways are Circadian entrainment andMetabolism

GPR143 Polyclonal Antibody, 100ul Centrifugal Filter Several pseudogenes have been associatedGPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.