N2DL3 Polyclonal Antibody, 20ul Variant Libraries This protein thus is thought

This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells

Alternatively spliced transcript variants have been found for KRT8

The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

Among its related pathways are Regulation of Microtubule Cytoskeleton

MIM 612725) (Stefansson and Brautigan| 2006

N2DL3 Polyclonal Antibody, 20ul Variant Libraries This protein thus is thoughtThe protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.