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PCNA Polyclonal Antibody, 100ul[BT-AP01367] Polyclonal Antibody Preparation 1 molecule alpha/2 molecules beta)

SKU: 60024499919

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PCNA Polyclonal Antibody, 100ul[BT-AP01367] Polyclonal Antibody Preparation 1 molecule alpha/2 molecules beta)The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have

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Description

1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor

Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine

Binds both upstream activators and downstream substrates in multimolecular complexes

is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion

and angiogenesis

PCNA Polyclonal Antibody, 100ul[BT-AP01367] Polyclonal Antibody Preparation 1 molecule alpha/2 molecules beta)The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have

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