ABC3C Polyclonal Antibody, 100ul Biomatrix Jackson-Weiss syndrome

Jackson-Weiss syndrome

The SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains

Expression of this gene may be downregulated in colon and rectal cancer

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RIN2 syndrome

ABC3C Polyclonal Antibody, 100ul Biomatrix Jackson-Weiss syndromeThis gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.